Profile & Experiences:

Dr. Mary Okesola is a Biochemist and Senior Lecturer in the Department of Chemical Sciences at Augustine University. She currently serves as the Acting Head of the Department (HOD), where she provides academic leadership and contributes significantly to teaching, research, and departmental administration.

Her research focuses on the biochemical and molecular investigation of medicinal plants for the treatment and management of diseases, particularly tumors and other chronic conditions. She integrates molecular biology, phytochemistry, and genomic techniques to understand the mechanisms through which bioactive compounds from medicinal plants exert therapeutic effects. Her work contributes to the discovery of safer and more effective natural products for disease management.

Dr. Okesola has published over 25 peer-reviewed articles in reputable international journals, reflecting her strong commitment to scientific research and innovation in biochemistry and natural product studies. She is actively involved in mentoring students, advancing scientific knowledge, and promoting interdisciplinary research in biochemical sciences.

Her academic interests include:

• Biochemistry
• Molecular Biology
• Phytochemistry
• Genomics and Disease Management
• Natural Product Research

She has also received several recognitions and awards for her contributions to research, academic excellence, and scientific development.

List of Published Articles in Learned Journals

i. Mary A. Okesola, Olufemi M. Familua, Charles O. Nwonuma, Marion O. Adebiyi, Olubanke O. Ogunlana, Omorefosa O. Osemwegie (2025). Leiomyomas: A Review on its Relationships with Transforming Growth Factor–βeta. NIPES - Journal of Science and Technology Research, vol 7, pp. 714–722. DOI: https://doi.org/10.37933/nipes/7.4.2025.SI83

ii.  Christogonus Chichebe Ekenwaneze, Suleiman Zakari, Emmanuel Chimuebuka Amadi, Mary Okesola, et al (2025). Association between CYP17A1 and HSD3B1 gene polymorphisms and testosterone levels in Nigerian prostate cancer patients. Scientific Reports 15, 33588. Available at: https://doi.org/10.1038/s41598-025-18752-x

iii.  Ajiboye, B.O., Famusiwa, C.D., Oghenemine, E.E…, M.A. Okesola, et al. (2025). Ameliorative effect of Hibiscus sabdariffa leaf flavonoid extract on the PSA/CEA/AKT/MMP-9 signaling pathway in benign prostatic hyperplasia-induced rats. Comp Clin Pathol (2025). https://doi.org/10.1007/s00580-025-03703-9

iv. Okesola M, Okesola J, Ogunlana O and Afolabi I (2022). Quality assessment of systematic literature on uterine fibroids: a systematic review. F1000Research, 11:1050. https://doi.org/10.12688/f1000research.124879.1

v. Mary A. Okesola, Abayomi E. Adegboyega, Adewale J. Lasisi, Folasade A. Bello, Olubanke O. Ogunlana, Israel S. Afolabi (2022). Elucidating the interactions of bioactive compounds identified from Camellia Sinensis plant as promising candidates for the management of fibroids - A computational approach. Informatics in Medicine Unlocked, 31(101002). https://doi.org/10.1016/j.imu.2022.101002

vi. Okesola, Mary Abiola, Ogunlana, Olubanke Olujoke, Afolabi, Israel Sunmola, Onasanya, Amos (2021). Ameliorative Effect of Zingiber officinale on Chemical Induced DNA Damage in Rats Using PCR Analysis. Biointerface Research in Applied Chemistry, 11(4): 11135–11144. https://doi.org/10.33263/BRIAC114.1113511144

vii. B.O. Ajiboye, B.E. Oyinloye, O.S. Oweroozeze, M.A. Okesola, I.L. Ekakitie, O.A. Ojo and A.P. Kappo (2021). Aqueous extract of Solanum macrocarpon Linn leaves abates hyperglycaemia and expression of glucose transporters gene in alloxan-induced diabetic rats. J Endocrinol Invest 44, 265–276. Available at https://doi.org/10.1007/s40618-020-01280-y

viii. Oluwafemi Adeleke Ojo, Mary Abiola Okesola, Lisa Ilobekemen Ekakitie, Basiru Olaitan Ajiboye, Babatunji Emmanuel Oyinloye, Precious Eseose Agboinghale, Amos Sunday Onikanni (2020). Gongronema latifolium Benth. leaf extract attenuates diabetes-induced neuropathy via inhibition of cognitive, oxidative stress and inflammatory response. Journal of the Science of Food and Agriculture, 100(12): 4504–4511. Available at: https://doi.org/10.1002/jsfa.10491

ix. Okesola, M.A., Ojo, O.A., Onikanni, S.A. et al. (2020). Ameliorative effect of Gongronema latifolium leaf extract on alloxan-induced diabetic cardiomyopathy in Wistar rats model. Comp Clin Pathol 29, 865–872. https://doi.org/10.1007/s00580-020-03134-8

x. Okesola MA, Ajiboye BO, Oyinloye BE, Osukoya OA, Owero-Ozeze OS, I Ekakitie L, Kappo AP (2020). Effect of Solanum macrocarpon Linn leaf aqueous extract on the brain of an alloxan-induced rat model of diabetes. J Int Med Res. 48(6):300060520922649. doi: 10.1177/0300060520922649

xi. Ajiboye B.O., Ojo O.A., Oyinloye B.E., Akuboh O., Okesola M.A., Idowu O., & Kappo A.P. (2020). In vitro antioxidant and inhibitory activities of polyphenolic-rich extracts of Syzygium cumini (Linn) Skeels leaf on two important enzymes relevant to type II diabetes mellitus. Pakistan Journal of Pharmaceutical Sciences, 33(2): 523–529. DOI: 10.36721/PJPS.2020.33.2.REG.523-529.1

xii. Ajiboye BO, Ojo OA, Oyinloye BE, Okesola MA, Oluwatosin A, Boligon AA, Kappo AP (2020). Investigation of the In Vitro Antioxidant Potential of Polyphenolic-Rich Extract of Artocarpus heterophyllus stem bark and its antidiabetic activity in streptozotocin-induced diabetic rats. J Evid Based Integr Med. 2020. doi: 10.1177/2515690X20916123

xiii. Ajiboye BO, Ojo OA, Fatoba B, Afolabi OB, Olayide I, Okesola MA, Oyinloye BE (2019). In vitro antioxidant and enzyme inhibitory properties of the n-butanol fraction of Senna podocarpa leaf. J Basic Clin Physiol Pharmacol. 31(1). doi: 10.1515/jbcpp-2019-0123

xiv. Ojo, A.B., Ojo, O.A., Okesola, M.A., Ajiboye, B.O. and Oyinloye, B.E. (2019). Garcinia kola extracts improve biochemical markers associated with erectile function: possible applications in clinical treatment? Acta Facultatis Medicae Naissensis. 36(1): 15–26. DOI: 10.2478/afmnai-2019-0002

xv. Ojo, O.A., Afon, A.A., Ojo, O.A., Ajiboye, B.O., Okesola, M.A., Aruleba, R.T., Adekiya, T.A. and Oyinloye, B.E. (2019). Spondias mombin L.: chemical fingerprints, inhibitory activities, and molecular docking on key enzymes relevant to erectile dysfunction and Alzheimer’s diseases. Journal of Food Biochemistry. e12772. DOI: 10.1111/jfbc.12772

xvi. Okesola, M. A., Ajiboye, B.O., Oyinloye, B. E. and Ojo, O.A. (2019). Neuromodulatory effects of ethyl acetate fraction of Zingiber officinale extract in rats with lead-induced oxidative stress. Journal of Integrative Medicine. 17(2): 125–131. https://doi.org/10.1016/j.joim.2019.01.002

xvii. Okesola, M.A., Ajiboye, B.O., Oyinloye, B.E. and Ojo, O.A. (2019). Effect of Zingiber officinale on biochemical parameters and cytogenetic analysis in lead-induced toxicity in experimental rats. Toxicology Mechanisms and Methods. 29(4): 255–262. DOI: 10.1080/15376516.2018.1558321

xviii. Ojo, O.A., Ojo, O.A., Ajiboye, B.O., Oyinloye, B.E., Akinyemi, A.J., Okesola M.A., Boligon, A.A., de Campos, M.M. (2018). Chromatographic fingerprint analysis, antioxidant properties, and inhibition of cholinergic enzymes of Irvingia gabonensis bark. Journal of Basic and Clinical Physiology and Pharmacology 29(2). https://doi.org/10.1515/jbcpp-2017-0063

xix. Ajiboye, B.O., Ojo, O.A., Akuboh, O.S., Okesola, M.A., Idowu, O. (2018). Anti-hyperglycemic and anti-inflammatory activities of Syzygium cumini leaves in alloxan-induced diabetic rats. Journal of Evidence Based Integrative Medicine. https://doi.org/10.1177/2515690X18770630

xx. Ojo OA, Ojo AB, Ajiboye BO, Olaiya O, Okesola MA, Boligon AA, de Campos MMA, Oyinloye BE, Kappo AP (2018). HPLC-DAD fingerprint analysis and antioxidant activities of Tithonia diversifolia leaves. Toxicology Reports. https://doi.org/10.1016/j.toxrep.2018.05.003

xxi. Ajiboye BO, Ojo OA, Akuboh OS, Okesola MA, Idowu OT, Oyinloye BE (2018). Protective effect of Syzygium cumini leaves on brain antioxidant status in diabetic rats. Jordan Journal of Biological Sciences. 11(2): 163–169. http://jjbs.hu.edu.jo/files/v11n2/Paper%20Number%207.pdf

xxii.  Ajiboye BO, Ojo OA, Okesola MA, Akinyemi AJ, Talabi JY, Idowu OT, Fadaka AO, Boligon AA, de Campos MMA (2018). In vitro antioxidant activities of Senecio biafrae extract. Food Science and Nutrition. 1–8. https://doi.org/10.1002/fsn3.749

xxiii.  Ajiboye BO, Akalabu MC, Ojo OA, Afolabi OB, Okesola MA, Olayide I, Oyinloye BE (2018). Inhibitory effect of Solanum macrocarpon leaves on key enzyme activities. Journal of Food Biochemistry. https://doi.org/10.1111/jfbc.12643

xxiv.  Ajiboye BO, Ojo OA, Okesola MA, Oyinloye BE, Kappo AP (2018). Ethyl acetate leaf fraction of Cnidoscolus aconitifolius: antioxidant potential and enzyme inhibitory activities. International Journal of Food Properties. 21(1): 1697–1715. https://doi.org/10.1080/10942912.2018.1504787